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"I've read that Benadryl can both raise and lower blood pressure - which is correct?"

ZocdocAnswersI've read that Benadryl can both raise and lower blood pressure - which is correct?


I am 47 years old and take 50mg at night to help fall asleep.


Benadryl is a medication that works by blocking the action of histamine, the mediator of common allergic reactions such as sneezing, itching, watery eyes, and runny nose. Benadryl itself is not a medication that directly acts to change blood pressure, but because of its potential effects on the vasculature and interactions with other drugs, it is recommended that this medication be taken with caution by those who have a diagnosis of hypertension and/or are on hypertension mediations. The best thing for you to do to protect your health is to discuss your use of Benadryl as a sleep aid (not uncommon, as this is the active ingredient in Tylenol pm) with your physician. He or she will be able to go over your health history and current medications to make sure that Benadryl is something that is safe for you to take. Unless you have wildly uncontrolled hypertension and are on many different medications, it is probably a perfectly safe medication to consider. However, it is always best to go over any prescription or over the counter medications with your physician and possibly your pharmacist to make sure there are not any concerning reactions or side effects that you should know about.

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