Thank you for your question about Acenac (also called aceclofenac). I would recommend that you discuss further management of your mother's medication with her primary care doctor
or the prescriber of the medication. As you have pointed out, Acenac is an NSAID medication (same class as ibuprofen). There are a number of adverse effects associated with chronic use of NSAIDs, and the risks of taking the medication need to be weighed against the benefits. Based on your description, your mother may be taking Acenac for her osteoarthritis, which is a common strategy to decrease inflammation and joint pain. Often times doctors
will recommend trying tylenol for pain relief in osteoarthritis before attempting NSAIDs, although many patients require NSAIDs for adequate symptom control. The major health concerns with chronic NSAID use involve the GI system, the kidneys, and the heart. NSAIDs can cause irritation of the stomach lining, possibly resulting in gastritis, ulcers, or bleeding. They can also also worsen kidney function and lead to dangerous elevations in potassium levels, usually in patients with preexisting kidney disease. Finally, NSAIDs can worsen high blood pressure, and there is data to suggest that many NSAIDs may increase the risk of heart attack or stroke in certain patients. There are strategies to monitor for and address these potential adverse effects, but the management of chronic NSAIDs can be complex and very patient specific. Therefore, I would strongly that your mother visit with her primary care physician
to discuss the risks and benefits of NSAIDs, in addition to any alternative medications that may be better suited to her needs.