Orange juice is an acidic liquid. Therefore, if you suffer from 'dyspepsia', meaning pain or heartburn with various foods, then orange juice may make this worse. The medical conditions that can underlie dyspepsia include too much acid production by the stomach, an inflammation of the stomach line ("gastritis"), or a stomach ulcer
. Dyspepsia is a symptom that should be medically investigated, because all of the possible causes have excellent medical treatments available. Furthermore, sustained acid reflux or heartburn symptoms can put one at risk of esophageal cancer later in life, and stomach ulcer can rarely cause life threatening bleeding
. In some people, orange juice may also act as a cholagogue, or agent which stimulates contraction of the gall bladder and flow of bile juice. Therefore, if you suffer from gall stones, orange juice may make your symptoms worse. As always the diagnosis and the management of your particular concern will require a physical examination by your personal physician. Setting up an office visit with your primary care doctor
might be advised.