The most likely explanation for your problem is a condition called dyshidrotic eczema. This is a type of eczema (eczema just means 'skin inflammation') in which blisters and peeling occurs on the palms of the hands or the sole of the feet. The condition is often itchy but not usually painful unless the open areas when blisters rupture become infected by bacteria. The exact cause of dyshidrotic eczema is unknown, although it is more common in people with other types of allergy (food or environmental allergies, asthma
In most cases, swings in environmental temperature, stress, and chemical contacts probably set off the flare that leads to the bad blistering. For most people, for example, thinking about any new soaps, shampoos, or fabrics is an important part of clearing up the flare. Additionally, in some cases, athlete's foot (fungal infection of the skin of the foot) might be a contributing factor that needs to be addressed.
The basic treatment for dyshidrotic eczema, in addition to eliminating any potential contact sources, is to keep the feet clean and dry (changing the socks frequently) and to apply a topical steroid cream. If it does not clear up with an over the counter steroid cream, you should see your dermatologist
or primary care doctor
to have something stronger prescribed.