I am sorry to hear that you have been having these symptoms for so long without good relief. Fortunately, it sounds like what you are dealing with is a relatively common condition known as dyshidrotic eczema
. This is an inflammatory condition of the skin of palms of the hands or soles of the feet in which small blisters form under the skin. The can be quite itchy and may coalesce to form areas of red, inflamed skin or peeling skin.
The mainstay of treatment of dyshidrotic eczema is to avoid the irritants and activities that tend to make it worse. These include various chemicals and cleaning products and, probably most importantly, immersing the hands in water (such as when washing dishes). To avoid this, it is recommended always to wear gloves when performing household chores and rubber gloves when washing dishes.
In addition to this, keeping the skin well moisturized multiple times a day (especially after each time you wash your hands) is important, and it is best to use a thick moisturizing ointment rather than a lotion. Finally, you may need a stronger steroid cream than over the counter cortisone, and your primary care doctor
should be able to prescribe this for you.