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Did I give my child cystic fibrosis?

I do not have cystic fibrosis but my child does. How did this happen? My husband doesn't have it either. How did we pass it down?
Cystic fibrosis is an autosomal recessive disease. This means that it is passed down from parents to their children, but that the parents don't necessarily have to have the disease themselves. Each parent has two sets of chromosomes (one each inherited from their own parents). Each chromosome contains genes, which can later become proteins manufactured in the body's cells. The particular gene that is affected in cystic fibrosis controls the production of a type of electrolyte transporter on the surface of certain cells. In order for a person to have cystic fibrosis, they need to have two mutated copies of the gene, not just one. In other words, your child inherited one defective gene from both you and your husband. Both you and your husband have one mutated version of the gene and one normal version of the gene. The chances of your child inheriting both of the mutated genes is 1 in 4. This is also the chance of all of your children developing the disease; having one child with cystic fibrosis does not change this probability in the future. For further information, you can talk with your primary care provider or seek out a genetic counselor.
This answer is for general informational purposes only and is not a substitute for professional medical advice.
If you think you may have a medical emergency, call your doctor or (in the United States) 911 immediately. Always seek the advice of your doctor before starting or changing treatment. Medical professionals who provide responses to health-related questions are intended third party beneficiaries with certain rights under Zocdoc’s Terms of Service.

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