Dr. Anthony Del Signore, MD, PharmD

Dr. Anthony Del Signore, MD, PharmD

Sinus Surgeon / Rhinologist
10 Union Sq E, Ste 5 B, New York, NY
4.85
“Dr. Signore was outstanding! He was knowledgeable, responsive, and provided the right tests and prescriptions promptly. He explained everything clearly. Highly recommend!”
Keshema W.January 14, 2026
Highly recommended
93% of patients gave this doctor 5 stars
Excellent wait time
94% of patients waited less than 30 minutes
New patient appointments
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Available appointments

What patients are saying

Overall rating

4.85

Average wait time

4.58

Bedside manner

4.89
“Dr. Signore was outstanding! He was knowledgeable, responsive, and provided the right tests and prescriptions promptly. He explained everything clearly. Highly recommend!”
Keshema W.January 14, 2026
“Del Signore is an excellent ENT, comprehensive and takes your issue seriously. My one piece of advice is: if anyone (including medical staff) is sick, they should wear a mask. It's not always clear that "what's going around" is the same bug.”
Initials hiddenLess than 6 months ago

About Dr. Anthony Del Signore

If you need to cancel your appointment within 24 hours of the scheduled time, please call the office. Dr. Anthony G. Del Signore is Assistant Professor in the Department of Otolaryngology and Director of Rhinology and Endoscopic Skull Base Surgery at Mount Sinai Beth Israel. He received his medical degree from the Warren Alpert School of Medicine at Brown University, completed residency in Otolaryngology-Head and Neck Surgery at Mount Sinai Hospital and fellowship in Advanced Rhinology and Endoscopic Skull Base Surgery at University of North Carolina, training with some of the preeminent leaders in the field. Specific clinical interests include medical and surgical management of chronic sinusitis, paranasal sinus and skull base tumors, orbital tumors, encephalocele repair, cerebrospinal fluid leaks (CSF), balloon sinuplasty, septoplasty, turbinate surgery and allergic disease. His particular training allows providing treatment via endoscopic minimally invasive techniques and office based procedures. His current research is focused on health outcomes following skull base surgery, implementation of sinus treatment protocols and surgical intervention, introduction and use of the ever changing technology in the practice of rhinology. Dr. Del Signore has been active in clinical research and has co-authored many textbook chapters and published manuscripts in rhinology, neurosurgery and otolaryngology. As a member of the Mount Sinai Beth Israel Rhinology and Endoscopic Skull Base Surgery team, Dr. Del Signore is committed to providing exceptional, direct-access patient care across Manhattan and Brooklyn, NY. He is available for short-notice and same-day consultations for patients with sinus disorders and skull base tumors and any other ENT complaints and is devoted to ensuring the longevity of his patients’ health and developing long-lasting relationships with them.

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Areas of expertise

This doctor's experience enhances their expertise in similar cases. Below are the conditions or surgeries they treat most frequently.
Chronic nose and throat inflammation due to allergies
Endoscopic sinus surgery
Chronic nose and throat inflammation due to allergies
Endoscopic sinus surgery

Office location

Dr. Anthony Del Signore, MD, PharmD also offers online video visits for patients
Mount Sinai Beth Israel ENT / Head and Neck Surgery
10 Union Sq E, Ste 5 B, New York, NY 10003

Education and background

Practice names

Hospital affiliations

  • Mount Sinai Beth Israel

Board certifications

  • American Board of Otolaryngology - Head and Neck Surgery

Education and training

  • Medical School - Brown University, Doctor of Medicine
  • Icahn School of Medicine at Mount Sinai, Residency in Otolaryngology and Head and Neck Surgery
  • University of North Carolina, Fellowship in Advanced Rhinology and Endoscopic Skull Base Surgery
  • University of Rhode Island, Doctor of Pharmacy

Professional memberships

  • Triological Society

Languages spoken

  • English
  • Italian

Provider's gender

Male

NPI number

1548420847

Patient reviews

All reviews have been submitted by patients after interacting with the practice.
Overall rating
4.85
Wait time
4.58
Bedside manner
4.89
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266 reviews
Most relevant
I was referred to him by family members. Yes, I would recommend him and his staff to anyone else with similar issues.
Verified patient
Staff was extremely nice and friendly. Would totally recommend this location and the doctor as well
Verified patient
Nice staff Doctor was nice and seemed knowledgeable I would recommend this doctor
Verified patient
Very competent doctor, was able to help me get my problem solved. Very friendly and dependable.
Verified patient
Dr. DelSignore is attentive, focused, intelligent and clearly communicates all options available .. I highly recommend him.
Verified patient
This is a doctor that has respect, dedication, and a high expertise for his craft. I am grateful for him and his staff.
Verified patient
Very easy experience. Called into the office before I finished the new patient forms. Dr answered all my questions.
Verified patient
Very professional. A little too serious - can use a bit more warmth. But he seems to be very good and that is most important
Very knowledgeable DR. He helped me understand the issue once I told him my symptoms and provided a prompt solution. (:
Verified patientVideo visit
He had a very calm, professional manner and he communicated each step of the appointment clearly. He's a great doctor!
Verified patient
Was great! He knows what he is talking about. He gave me some recommendations and I am supposed to see him again soon.
Verified patient
Nice guy, super efficient. He explained what was wrong, and outlined a way to fix it. I am going back to see him.
Verified patient
He was great! So nice and thorough, and he explained everything to me. It was a great experience.
Verified patientVideo visit
Super nice Doctor!!! Difficult to get appointments with him but definitely worth the wait
Verified patient
Dr. Del Signore was very nice, listened to me, asked a lot of questions and was patient.
I feel much better. Dr. Del Signore was understanding, compassionate and knowledgeable.
Verified patient
Professional and clear communicator. Took my input into account.
Lo máximo con dr y ser humanos con su paciente siempre preupado por su pacientes
Verified patient
Extremely professional and easy to speak with. Looking forward to next visit.
Every time I booked with Zocdoc very satisfied very professional
Verified patient
Appointment took 2 hours and I saw him for less than 5 minutes. Not good!
Dr. Del Signore was a pleasant and informative Dr. Highly recommend
Verified patient
Amazing doctor. Really cares takes his time and is very thorough
Video visit
Was great and very helpful! I'd highly recommend Dr. Del Signore
Verified patientVideo visit
He was very helpful and made me feel positive about my situation
Verified patient
Very professional. Would recommend to a friend or family member.
Verified patient
One of the most detailed explanations I've received from a doc
Great bed side manner and very thorough and knowledgable!
Verified patient
Great bed side manner. Highly recommend this physician
Great doctor. Able to listen and quick to understand.
Verified patient
Dr. Signore was outstanding! He was knowledgeable, responsive, and provided the right tests and prescriptions promptly. He explained everything clearly. Highly recommend!
Verified patient
Del Signore is an excellent ENT, comprehensive and takes your issue seriously. My one piece of advice is: if anyone (including medical staff) is sick, they should wear a mask. It's not always clear that "what's going around" is the same bug.
Really great experience! He addressed my problem right away, gave me a couple prescriptions and I walked away with very clear next steps of things to try for my sinus issues. Overall a very effective visit, which is rare in my experience with doctors
Very organized and professional team
Verified patient
Dr. Del Signore was very kind and professional. He listened to everything I had to say and provided me with guidance and prescription to help with my problem. This was my first time going to an NET doctor and I would highly recommend to anyone looking to go.
Verified patient
Doctor was nice enough. However when I wrote back a few days later complaining of side effects from the medication they gave me - I was repeatedly told to go to the ER. My symptoms were nowhere near something that would call for an ER visit. I just wanted to try different medication. Very dismissive. I’m not sure I would recommend.
From start to finish, and 5 star experience. When you're feeling awful and haven't gotten relief for a while, this was a very pleasant surprise. All paperwork was digital that I filled out from home. Staff greeted me with a smile and reviewed the paperwork quickly. Taken 30 minutes early. Staff was very empathetic, read the paperwork, and was super thorough. The doctor is young, intelligent, and ticked off all the questions I had written down before coming. At no point did I feel rushed. His staff met with me afterward to go over treatment in detail and provided step by step instructions to me. They encouraged me to call at any point. The doctor saw me on the way out and said to DM him in a week to let him know how I'm doing. Location is ideally located a minute walk from the 14th Street station with many subway lines. Love this practice! I highly recommend it.
Verified patient
Excellent doctor. He took his time to check everything and test. After discussing wanted to go to surgery route, instead of him doing it himself he referred me to a colleague of his since they were more skilled at certain part for the specific surgery I needed. The referred doc/surgeon was as excellent as well and everyone was super nice. My experience with Mount Sinai doctors, nurses and other workers has always been very positive.
Verified patient
Really great experience from having an easy check-in, minimal wait time, and great discussion with Dr. Del Signore and his resident/supporting doctor. We arrived at a good next step to confirm the diagnosis and, hopefully, get some reprieve. Highly recommended.
Verified patient
Timely, friendly, rational, responsive after appt
Verified patient
Dr. Del Signore was friendly and communicated clearly. He was attentive to my issues and offered several solutions. He and his staff saw me shortly after my arrival. I would highly recommend him to any potential patients.
Verified patient
The visit was very pleasant, and the doctor was competent and friendly. He answered all my questions and clarified in detail all my doubts. I would definitely recommend him.
Verified patient
they made me feel welcome and comfortable
Verified patient
NYU building is Amazing . The Fantastic Receptionist start the appointment off Perfect with their warm & professional welcome. The ENT Doctor is Very Knowledgeable & provided excellent care for me as a new patient. Left feeling better than I came , I’m Glad I made the appointment.
Verified patient
Great experience. Nice office, friendly staff. Dr. Anthony was knowledgeable about my condition, and gave me a subscription quickly. Would recommend!
Verified patient
Amazing first-time patient experience with Dr. Del Signore!!! He's absolutely fantastic in every way. He answered every question I asked with no hesitation and explained things extra clearly to me. He also let the office staff know I was waiting for too long and really sped up the exit process for me. Will highly recommend him to friends and family.
Verified patient
Dr. Signore and his assistant are very nice - they listened to my concerns and diagnosed my problem quickly. I hope the treatment will be effective.
Verified patient
Dr. Anthony Del Signore is a ENT but specializes in the nose, but I was there for my ears. I explained to me that his specialty was the nose, however he said he is also a general ENT and he did attended to me with much care and even examined my nose due to an issue I told him of?? he was totally cool and addressed my issues and concerns and gave me some great insight on how to care for my nasal problem even though that’s not what I went for. I would definitely recommend him to my friends and family. His bedside manner was very pleasant. He listened and gave his best recommendations for my health issues, to which I appreciated. The entire staff was friendly, friendly and courteous, from the receptionist to the other nurses that were busy with other patient. The nurse the attended to me before Dr. Del Signore had me laughing. My visit was totally different and awesome. Thanks guys you’re an amazing team.??
Verified patient
I felt uncomfortable with this doctor, definitely a little creepy. He got the job done but I was certainly not comfortable during the appointment.
Dr. Anthony Del Signore was very attentive and patient with me as I shared my ENT concerns and he asked several detail oriented questions to understand more about them. With doctors I usually feel rushed out of the door, but Dr. Anthony Del Signore did not cause that feeling - he was very kind, affirmative, and empathetic to my concerns and provided excellent holistic insights and recommendations for relief.
Verified patientVideo visit
Frequently asked questions

How soon can I make an appointment with Dr. Anthony Del Signore?

Generally, Dr. Anthony Del Signore has appointments available on Zocdoc within 1 week. You can see Dr. Del Signore's earliest availability on Zocdoc and make an appointment online.

Is Dr. Anthony Del Signore accepting new patients?

Dr. Anthony Del Signore generally accepts new patients on Zocdoc. You can see Dr. Del Signore's earliest availability on Zocdoc and schedule an appointment online.

Does Dr. Anthony Del Signore accept my insurance?

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Can I make an appointment with Dr. Anthony Del Signore online?

Yes, you can make an appointment online with Dr. Del Signore using Zocdoc. It’s simple, secure, and free.

Which hospital is Dr. Anthony Del Signore affiliated with?

Dr. Anthony Del Signore is affiliated with Mount Sinai Beth Israel.

What practice does Dr. Anthony Del Signore work with?

Where is Dr. Anthony Del Signore's office located?

Dr. Anthony Del Signore has 2 office locations in New York, view full addresses on Dr. Del Signore's profile.

Which board certifications does Dr. Anthony Del Signore have?

Dr. Anthony Del Signore is certified by American Board of Otolaryngology - Head and Neck Surgery.

What are common reasons for patients to see Dr. Anthony Del Signore?

Dr. Anthony Del Signore frequently sees patients for Nasal Allergies, Nasal Congestion, Nose Problems, Nose Surgery, and Sinus Problems / Sinusitis. You can see other visit reasons for Dr. Anthony Del Signore on their profile.

What languages does Dr. Anthony Del Signore speak?

Dr. Anthony Del Signore speaks English and Italian.

How do patients rate Dr. Anthony Del Signore in reviews?

266 patients have reviewed Dr. Anthony Del Signore. The overall rating for this doctor is 4.85/5. They have a 4.89/5 rating for bedside manner and a 4.58/5 rating for wait time. You can read individual reviews and ratings on their profile.

Zocdoc›Sinus Surgeons/Rhinologists›Dr. Anthony Del Signore, MD, PharmD