“Great visit with the PA. The front office staff wasn't there so Dr. O'Keefe had to do everything himself. But after waiting to check in, my time wirh him was really good. Would definitely recommend.”
Maria D.June 8, 2026
Patients often return
More patients return than other providers in the area
Highly recommended
92% of patients gave this doctor 5 stars
Excellent wait time
95% of patients waited less than 30 minutes
New patient appointments
Appointments available for new patients on Zocdoc
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The office partners with Zocdoc to schedule appointments
“Great visit with the PA. The front office staff wasn't there so Dr. O'Keefe had to do everything himself. But after waiting to check in, my time wirh him was really good. Would definitely recommend.”
Maria D.June 8, 2026
“Shawn was great, straight talk to the point. He provided quick advice to help with my problem.
I highly recommend this practice.”
Michael C.March 16, 2026
About Shawn OKeefe
Shawn, a highly experienced and board-certified Physician Assistant at Twenty-One Medical, is dedicated to delivering exceptional healthcare to the Charlotte community and surrounding areas.
With over two decades of expertise in orthopedics and extensive experience in urgent care, family medicine, weight loss, men’s health, and sports-related injuries, Shawn brings a diverse medical background to his practice. He earned a Master of Science in Education specializing in Sports Medicine from the University of Miami, a Master of Public Health, and a Master’s in Physician Assistant Studies from Nova Southeastern University. His comprehensive education and commitment to patient care make him a trusted provider for individuals and families throughout the Charlotte area.
Over the past three years, Shawn has expanded his practice to include family medicine, urgent care, weight loss, men’s health, DOT physicals, and Botox treatments. This broad experience enables him to confidently address a wide range of medical conditions beyond orthopedics.
The office has also grown its wellness and aesthetics program to offer Botox, medical weight loss, Body Sculpting with Emsculpt NEO, and Clarity II laser treatments, including laser hair removal, laser facials, and therapies for pigmented and vascular lesions. Additionally, the clinic features a TED system for hair regeneration to assist with male and female pattern balding and alopecia.
Having lived in Charlotte for over 16 years, Shawn has established deep roots in the community. As a former United States Marine, he embodies discipline, dedication, and compassion in both his professional and personal life.
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In-network insurances
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National Commission on Certification of Physician Assistants
Education and training
Nova Southeastern University, Master's in Physician Assistant Studies
Nova Southeastern University, Master's in Public Health
University of Miami (MSEd)
Professional memberships
American Academy of Physician Assistants
Languages spoken
English
Provider's gender
Male
NPI number
1063469864
Patient reviews
All reviews have been submitted by patients after interacting with the practice.
Overall rating
4.81
Wait time
4.72
Bedside manner
4.90
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165 reviews
Most relevant
My issues were thoroughly examined and the options for treatment meticulously explained. I will definitely go back
December 19, 2025Daniel H.Verified patient
Great experience! The staff were wonderful and the doctor was very polite and respectful and answered all of my questions.
Less than 1 year agoInitials hidden
Came in for a physical. He was thorough and friendly, highly recommend!
June 17, 2026John H.Verified patient
Friendly staff, PA well versed in his area and wonderful bedside manner which all in all resulted in excellent care.
More than 1 year agoRT
I had a wonderful experience here! A smooth and quick process and all questioned were answered. Thank you again!
More than 1 year agoON
Very knowledgeable, attentive, great listener. Will recommend to all looking for a primary care physician.
December 10, 2024Nicole R.Verified patient
Had a great experience. Will be recommending to friends and family.
March 9, 2026Peter D.Verified patient
I am getting the help I need and have a follow up appointment in a month.
May 16, 2025priscilla T.Verified patient
Very pleasant experience. Definitely will be going back!
More than 1 year agoInitials hidden
Great service from all employees. Will definitely recommend others .
More than 1 year agoAC
Excellent communication and knowledgeable very proactive
December 13, 2024Stacie W.Verified patient
Great visit with the PA. The front office staff wasn't there so Dr. O'Keefe had to do everything himself. But after waiting to check in, my time wirh him was really good. Would definitely recommend.
June 8, 2026Maria D.Verified patient
I waited 20 minutes before anyone knew i was in the lobby. I even called the office 3 times to try to get someone to come to the lobby to check me in. I could hear people in the building but nobody came to greet me. Finally i yelled hello a few times for someone to hear me— the doctor came to the front—upon speaking to the doctor he seemed as if he didn’t want to take me and tried to talk me out of getting seen and going somewhere else. I drove to pineville for nothing.
Less than 1 month agoInitials hidden
I was almost at the office and was told the office was closed till after my appointment and would have to reschedule or wait and it would be a long wait
Less than 3 months agoInitials hidden
Shawn was great, straight talk to the point. He provided quick advice to help with my problem.
I highly recommend this practice.
March 16, 2026Michael C.Verified patient
The provider was professional. The facility was short staffed and when I called about my lab order, there didn't seem to be much friendliness from the desk person which bothered me.
Less than 6 months agoInitials hidden
First time using this service, everything was on time. The office was clean and exam room set up. He listened and explained everything clearly and thoroughly. I will be using his services as my regular medical needs come up.
March 5, 2026James K.Verified patient
Very professional
February 26, 2026Tyson S.Verified patient
Loved the experience!
February 21, 2026Lightness N.Verified patient
Dr. Shawn was very easy going and I didn't feel intimidated talking to him for the sensitive issue that I went for today. He was very reassuring in his diagnosis of me and made it easy to agree to a follow up appointment. I would definitely recommend him to any in the area close by looking for consultation.
February 3, 2026Ben D.Verified patient
It was a relief being examined by Shawn today…. He calmed my fears of being fractured and badly injured. Thank you for your friendly, professional care Shawn.
January 29, 2026Rosemary S.Verified patient
Great listener and effective doctor!
January 13, 2026Jordan L.Verified patient
It was great experience and staff was great.
November 12, 2025Jevon S.Verified patient
He did great! Straight to the point!
October 21, 2025Brandon P.Verified patient
I had a very pleasant experience for my first visit! Dr. O'Keefe is awesome! He listens to your concerns and puts you at ease, and comes up with a treatment that works for everyone! I'm very happy I stumbled across this app and extremely pleased at who I picked to be my new family care provider!
September 26, 2025Paige S.Verified patient
Very clear and to the point when it came to everything relating to my visit as well as in my follow up appointment, he and his staff were extremely friendly.
Less than 1 year agoJustin M.Verified patient
The provider is kind, respectful, and courteous.
He goes above and beyond to make sure his patients concerns are addressed.
He truly cares about his patients. I highly recommend him. You will not be disappointed.
September 18, 2025Carol J.Verified patient
Great guy! Got me in and out.
Definitely knows his practice. Considering him as my PCP after speaking with him. He genuinely cares about his patients health.
July 2, 2025Initials hidden
Shawn was great. I established care and have a follow up to review things. Referred me to who I needed to get things checked out. Overall good experience.
June 17, 2025Logan W.Verified patient
This office was efficient and clean
May 9, 2025Soreida T.Verified patient
Great place for everything medical. They do it all here. Dr. OKeffe has a great bedside manner. He's patient, thorough and knowledgable. Give them a try-you won't be disappointed
April 24, 2025Barbara K.Verified patient
Great experience. Made him my primary provider.
February 21, 2025James L.Verified patient
Shawn was great. Very through and knowledgeable.
February 16, 2025Annie P.Verified patient
I was hesitant and nervous trying to find a new provider online but glad I continued my search in finding and using zocdoc. I am very pleased with the doctor I chose. I would definitely recommend it for anyone in need of a provider that actually cares about their patients.
January 29, 2025Rachael O.Verified patient
I had a surprise having to "check out" on a screen with a remote scheduler in Wisconsin. But hey, that's the age we're in. Otherwise I'm glad to have a primary care physician, as I just moved from another state and doctors who take new patients are hard to find.
January 22, 2025Robert K.Verified patient
Very thorough. Dr. O'Keefe went through my list of problems and they filled in the gaps by checking all systems. Being able to get an X-ray on the spot was impressive. His prescription to the drugstore went quickly. I'm looking forward to a follow up visit.
January 16, 2025Robert K.Verified patient
I have found most PAs very efficient and effective in their approach to health maintenance. Dr OKeefe was true to form with a staff that mirrored him.
More than 1 year agoMarc T.Verified patient
My experience with Shawn and his staff was excellent. From start to finish, everything was smooth and communication was good. Everything I needed was taken care of. I highly recommend Shawn.
November 26, 2024Martha M.Verified patient
The doctor and staff went above and beyond with seeing me asap!! Bedside manner was amazing, something that has been lacking since covid. I felt comfortable and safe. I plan on bringing my son’s here… that’s how happy this visit made me. Thank you so much!!
November 21, 2024Lisa T.Verified patient
Dr. Shawn went above and beyond with making me feel comfortable and at ease with my health concerns. His staff was so nice, from the phone calls to in person. I highly recommend Dr. O’Keefe and his staff and will be bringing my sons here.
More than 1 year agoLT
Definitely a great experience
November 19, 2024Jermaine J.Verified patient
Overall Shawn and the staff at the office are great. I was seen pretty quickly and was able to be taken of. I was able to get an annual check up done quick and easy. Thanks again Shawn!
November 17, 2024Uchenna N.Verified patient
Excellent customer service. Very professional and courteous. Doctor was easy to talk with and provides me with some relief for my health issues
November 12, 2024Olivia N.Verified patient
Dr. Keefe treated my cold
and gum infection quickly and professionally. He called in the prescription, which was waiting for me when I arrived.
I felt better right away and was able to continue my visit with my brother and his family.
More than 1 year agoAC
The attentiveness & professionalism of the staff is impeccable ! From the front desk receptionist , the providers bed side manners & throughout the process of my first appointment . I am making this provider my PCP. I truly recommend this office.
November 3, 2024Michael T.Verified patient
June 9, 2026Juste I.Verified patient
Less than 1 month agoInitials hidden
Less than 1 month agoInitials hidden
May 29, 2026Christopher K.Verified patient
Less than 3 months agoInitials hidden
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Frequently asked questions
How soon can I make an appointment with Shawn OKeefe?
Generally, Shawn OKeefe has appointments available on Zocdoc within 1 week. You can see Shawn OKeefe's earliest availability on Zocdoc and make an appointment online.
Which board certifications does Shawn OKeefe have?
Shawn OKeefe is certified by National Commission on Certification of Physician Assistants.
What are common reasons for patients to see Shawn OKeefe?
Shawn OKeefe frequently sees patients for Annual Pap Smear / GYN Exam, Annual Physical, ENT Consultation, Illness, and Orthopedic Consultation. You can see other visit reasons for Shawn OKeefe on their profile.
165 patients have reviewed Shawn OKeefe. The overall rating for this doctor is 4.81/5. They have a 4.9/5 rating for bedside manner and a 4.72/5 rating for wait time. You can read individual reviews and ratings on their profile.