Dr. Karen Burke, MD, PhD

Dr. Karen Burke, MD, PhD

Dermatologist
429 E 52nd St, River Court, New York, NY
4.65
“I had an excellent experience with Dr.Burke. As soon as I walked into the office, the front desk was very attentive and welcoming. Dr. Burke was (is) very knowledgeable in all aspects of dermatology and overall medicine. I never felt rushed during my appointment and every concern was thoroughly addressed. Dr. Burke maintains a high standard of care , is trustworthy and is passionate about her work. I highly recommend this dermatologist .”
Barbara C.March 5, 2026
New patient appointments
Appointments available for new patients on Zocdoc

Book an appointment for free

The office partners with Zocdoc to schedule appointments

Scheduling details

  1. See if they are in network

What patients are saying

Overall rating

4.65

Average wait time

4.27

Bedside manner

4.78
“I had an excellent experience with Dr.Burke. As soon as I walked into the office, the front desk was very attentive and welcoming. Dr. Burke was (is) very knowledgeable in all aspects of dermatology and overall medicine. I never felt rushed during my appointment and every concern was thoroughly addressed. Dr. Burke maintains a high standard of care , is trustworthy and is passionate about her work. I highly recommend this dermatologist .”
Barbara C.March 5, 2026
“Dr. Burke, This is the first time I saw Dr. Burke. I was impressed with how much time she spent with me. Explained what she found and appropriate procedures. Very pleasant, attentive did not try to push products or unnecessary procedures. Waited about 10-15 minutes before I was seen. I recommend Dr. Burke.”
Rebecca K.November 17, 2025

About Dr. Karen Burke

Dr. Karen Burke, MD, PhD, is a Board-Certified Dermatologist and research scientist with extensive training, including a Doctor of Medicine from New York University, a Dermatology Residency at New York University, and a PhD in Biophysics from Cornell University, where she also completed a fellowship. She has been recognized as a “Top Doctor – NY Metro Area” by Castle-Connolly for 24 years. Dr. Burke treats all adult and pediatric dermatologic problems involving the skin, hair, and nails, specializing in cosmetic medical antiaging skincare and treatments such as fillers, Botox, radiofrequency, and laser, as well as skin cancer. She is known for her caring patient relationships, non-rushed consultations—often spending more than one hour with new patients—and meticulous attention to detail, especially in screening for abnormal moles, precancers, and skin cancer. She manages a wide range of skin conditions including acne, rosacea, eczema, itching, moles, aging skin, skin precancer and cancer, hair loss, hives, allergies, psoriasis, warts, herpes, shingles, discoloration, excess sweating, fungal infections, nail abnormalities, and other skin diseases, as well as cosmetic concerns. As a Clinical Professor of Dermatology at Icahn School of Medicine at Mount Sinai, NY, Dr. Burke researches topical antioxidants to reverse skin aging and prevent skin cancer, holding two patents in this area. She also investigates a novel T-cell immunotherapy treating all cancer types, initially focusing on metastatic melanoma, prostate, lung, and ovarian cancers in terminal patients. Dr. Burke was among the first to demonstrate that topical retinoic acid effectively treats photodamage and conducted pioneering studies on collagen and hyaluronic acid implants for wrinkles and scars. She has also researched fat structure and metabolism. My goal is to provide comprehensive, compassionate care tailored to each individual's unique needs.

Is this doctor in your insurance network?

Enter your insurance carrier and plan
  1. choose insurance

In-network insurances

99% of patients have successfully booked with listed insurances
Dr. Karen Burke has 200+ in-network plans.

Areas of expertise

This doctor's experience enhances their expertise in similar cases. Below are the conditions or surgeries they treat most frequently.
Benign or precancerous skin growths
Benign or precancerous skin growths

Other popular visit reasons

Acne
Allergy Consultation
Annual Skin Screening
Dermatology Consultation
Dermatology Surgery
Pediatric Itching
Rash
Sexually Transmitted Infection (STI)
Acne
Allergy Consultation
Annual Skin Screening
Dermatology Consultation

Office location

Karen E Burke, M.D. Ph.D.
429 E 52nd St, River Court, New York, NY 10022

Education and background

Practice names

Hospital affiliations

  • The Mount Sinai Hospital

Board certifications

  • American Board of Dermatology

Education and training

  • Medical School - New York University, Doctor of Medicine
  • New York University, Residency in Dermatology
  • Cornell University, PhD in Biophysics
  • Cornell University (Fellowship)
  • Rockefeller University (Fellowship)

Professional memberships

  • Women's Dermatologic Society
  • Skin Cancer Foundation
  • The New York Stem Cell Foundation
  • Women's International Forum

Awards and publications

  • Castle Connolly Top Doctor
  • Castle Connolly Top Doctor 2001-2022
  • Health Hero, 2018 Power Women in Business

Languages spoken

  • English
  • French
  • German

Provider's gender

Female

NPI number

1629286083

Patient reviews

All reviews have been submitted by patients after interacting with the practice.
Overall rating
4.65
Wait time
4.27
Bedside manner
4.78
Trust Banner Shield
Your trust is our top concern, so providers can't pay to alter or remove reviews. We also don't publish reviews that contain any private patient health information. Learn more here
234 reviews
Most relevant
Dr. Burke is the best. In just one short month, my skin has improved dramatically. I am so glad I found her through Zoc Doc.
Verified patient
Excellent doctor!! I love her. So thorough, patient and compassionate. All doctors should be like her. Simply amazing...
Verified patient
It was great meeting Dr. Karen Burke. She was very thorough and addressed all my dermatological issues. Tanya
Verified patient
Long wait however once seen, the Dr. was extremely attentive & answered all questions and concerns. Would recommend.
I loved visiting Dr. Burke. She is caring and take her time to learn to know you and find the right treatment.
Verified patient
She was very attentive and considerate, making sure to get my prescription in ASAP before the pharmacy closed.
Verified patient
She is always very thorough when examines you. Listens attentively. We’ve been with her for over 20 years.
Verified patient
Visit was great. Took the time to address all my concerns and gave treatments during the first visit.
She is a clear pro in her field. She blew me a kiss on my way out, which made my whole night.
Verified patient
very knowledgeable and took her time to check me and explain to me clearly what i had.
Verified patient
Dr. Burke is very experienced, friendly, and articulate. I was thoroughly impressed!
Verified patient
HIGHLY recommend! Best derm visit in NYC ever. So grateful I discovered Dr. Burke.
Verified patient
Very personalized, excellent dermatolgist, extremely helpful and very comprehensive.
Will try to push her products on you, no matter what you’re there for.
It was great! Dr. Burke is incredibly knowledgeable and thourough.
I have been going to Dr. Burke for years and she is the best!
Verified patient
Very friendly, very knowledgeable and took great care of me.
Verified patient
Very knowledgeable, attentive, meticulous, professional.
Verified patient
She was great! Extremely knowledgeable and thorough.
I had an excellent experience with Dr.Burke. As soon as I walked into the office, the front desk was very attentive and welcoming. Dr. Burke was (is) very knowledgeable in all aspects of dermatology and overall medicine. I never felt rushed during my appointment and every concern was thoroughly addressed. Dr. Burke maintains a high standard of care , is trustworthy and is passionate about her work. I highly recommend this dermatologist .
Verified patient
Dr. Burke, This is the first time I saw Dr. Burke. I was impressed with how much time she spent with me. Explained what she found and appropriate procedures. Very pleasant, attentive did not try to push products or unnecessary procedures. Waited about 10-15 minutes before I was seen. I recommend Dr. Burke.
Verified patient
Dr. Burke is such a caring physician! She really goes out of her way to listen to your full story and remember little details about you. I felt comfortable with her from the first visit. She never rushes her patients, and she even takes extra time to get to know them and their specific goals better - something refreshing and rare nowadays in medical practices. I would highly recommend as a provider and person!
Verified patient
Dr. Karen's scan of my skin is very professional and detailed as always. Her expect medical opinion is also second to none. You are in excellent hands if you visit Dr. Burke.
Verified patient
It was wonderful! Dr. Burke paid attention to all my concerns and worries. She gave me guidance and advices on my skin’s needs as well as handouts and information to take home for self care. I am so happy I found her as my Dermatologist.
Verified patient
Was given great care and attention.
Verified patient
Dr. Burke is extremely smart and knowledgeable, she cares a lot, and she is a good and nice person. I always enjoy my visits with her.
Verified patient
Dr. Burke is the best!
Verified patient
My concerns were discussed and my questions were answered. The receptionist was nice and the doctor was thorough and kind. The office and waiting area are clean and comfortable. A few issues. 1. She was 15 minutes late. 2. When she arrived, she was instructing the new receptionist about how to do things, further delaying my appt. 3. All the records are on paper, and she takes handwritten notes, so the entire process was very slow, taking 2 hours. 4. She is chatty. Not an issue if you don’t have anywhere to be, but if you need to be in and out quickly, not sure I’d recommend this doctor. 5. I had to call my insurance company in the waiting room to figure out my copay because she didn’t know how to interpret my insurance card. 6. Hard to find her office as it’s within an apartment complex. Overall, she clearly knows her stuff and enjoys her work. She didn’t peddle the products she sells too much and gives good skincare advice. I liked her and now I know what to expect if I go back.
Verified patient
Excellent doctor. Asks the right questions and listens carefully. I did not feel rushed. I will absolutely return and have already recommended a friend To see Dr. Burke.
Verified patient
Dr. Burke is a kind, knowledgeable, and experienced doctor. She genuinely cares about the people she treats, and it shows in the care she provides. Very rare find as far as doctors and people in general come, I couldn’t recommend her enough!
Verified patient
I had an amazing experience with Dr.Karen Burke, She is kind thoughtful, and went above and beyond for and making sure I had had the proper after care and spending more time with me than any other doctor ever has. Her thoroughness and dedication makes her stand out as a doctor.
Verified patient
I highly recommend Dr. Burke.
Verified patient
I was called day before to move my appointment 30 minutes later, and I agreed. Once I arrived I’ve waiting for 40 minutes. Never seen the doctor. I’ve asked front desk how much longer should I expect to wait after I filled out everything and the answer was 15 minutes. After I waited those 15 minutes I checked with Front desk for updates, and I’ve been told Doctor should see me in about 15 minutes. I left without seeing doctor. Very upsetting experience.
Verified patient
Outstanding.
Dr. Burke is amazing - extremely knowledgable, patient, caring, explains clearly what the issues are, and solves them. She always goes above and beyond for her patients. I would recommend her to anyone!
Dr. Burke was thorough, listened to my concerns, completed some services and advised on aftercare. She also has a friendly demeanor.
Verified patient
Dr. Burke is extremely knowledgeable, honest and easy to talk to. Unlike most doctors today, she gives you so much quality time. I never feel rushed. She listens and addresses all my concerns. I've been a patient of hers for over 20 years, and I will never go elsewhere. I also highly recommended her microdermabrasion scrub. Its the best skin care product I have every used.
Verified patient
Dr. Burke has a deep knowledge of her field and is radiant with kindness and intelligence. Wonderful dermatologist with impeccable bedside manner.
Verified patient
I would absolutely recommend Dr. Karen. She was so thorough and really took her time with the appointment. Additionally, Dr. Karen recommend products for my needs and gave insights on all of my concerns. She was so warm and friendly, will definitely return!
Verified patient
Dr. Burke phoned me no more than 5 minutes after I booked the appointment on Zocdoc to confirm our appointment. She even gave me her cell number. She is thorough, kind, efficient and a fine physician.
Verified patient
I've been Dr. Burke's patient for a good ten years. I recommend her unreservedly. A savvy lady. Very kind and amazingly thorough. --B. F.
Dr. Burke is amazing!
Verified patient
Very friendly and extremely competent
Lovely lady very knowledgeable on her work, she knows all the products needed for hair growth and acne removal so i’d highly recommend 10/10
Verified patient
My local doctor couldn’t see me for 3 weeks. Dr. Burke had 1 appointment left & stayed late to help me (on my first visit). I would definitely recommend her!
Verified patient
Doctor arrived 30 minutes late. Office was locked. Made us wait 1.5 hours while she turned on the lights, did paper work. Appointment was for 3pm, she saw us after 5pm and then kept on rushing because she had more patients coming. She was calling patients while we were waiting to ask them if they could come in that day instead of next week. Instead of looking at the issues on hand, the entire time she tried to sell her own line of skincare. No issue was addressed.
Verified patient
Was called 11 (!) times prior to my appointment, four of which were on the day of the appointment after I’d already confirmed twice to ask if I could come in earlier. Thought the insistence on calling was strange, as every other doctor I’ve seen has had a text/email system for checking in, but realized once I arrived that nothing was digital. Check in was a lengthy process; the forms I filled out had gone so long without being updated that the demographics section listed “white”, “black”, and “oriental” as the options for race. As for treatment itself, had an acne medication, full-body exam, blood work, vitamins and anti-aging soap pushed on me, none of which had anything to do with the concerns I was there to treat. All in all, I was at the office for an hour and forty five minutes (I’ve received treatment for the same issue before in ~30). I’d recommend this place if you have good insurance and want to experience a Twilight Zone time machine, otherwise, look elsewhere.
Easily the best dermatologist I’ve been to in the city. She listened to all of my concerns and gave me a plethora of information that no other doctor has ever bothered to share with me. She is clearly extremely knowledgeable and if you’re looking to actually learn more about your conditions, she is the doctor to see. Spent over an hour with me addressing every question I had during a standard yearly exam.
Verified patient
Amazing dermatologist!
Verified patient
Doctor was wonderful! I’m so glad I was able to see her. Dr. Burke answered all my questions and offered options for every concern. She’s thoughtful and thorough!
Verified patient
Frequently asked questions

How soon can I make an appointment with Dr. Karen Burke?

Generally, Dr. Karen Burke has appointments available on Zocdoc within 1 week. You can see Dr. Burke's earliest availability on Zocdoc and make an appointment online.

Is Dr. Karen Burke accepting new patients?

Dr. Karen Burke generally accepts new patients on Zocdoc. You can see Dr. Burke's earliest availability on Zocdoc and schedule an appointment online.

Does Dr. Karen Burke accept my insurance?

Choose your insurance plan to verify if Dr. Burke is in-network.

Can I make an appointment with Dr. Karen Burke online?

Yes, you can make an appointment online with Dr. Burke using Zocdoc. It’s simple, secure, and free.

Which hospital is Dr. Karen Burke affiliated with?

Dr. Karen Burke is affiliated with The Mount Sinai Hospital.

What practice does Dr. Karen Burke work with?

Where is Dr. Karen Burke's office located?

Dr. Karen Burke's office is located at 429 E 52nd St, New York, NY 10022.

Which board certifications does Dr. Karen Burke have?

Dr. Karen Burke is certified by American Board of Dermatology.

What are common reasons for patients to see Dr. Karen Burke?

Dr. Karen Burke frequently sees patients for Acne, Allergy Consultation, Annual Skin Screening, Dermatology Consultation, and Sexually Transmitted Infection (STI). You can see other visit reasons for Dr. Karen Burke on their profile.

What languages does Dr. Karen Burke speak?

Dr. Karen Burke speaks English, French, and German.

How do patients rate Dr. Karen Burke in reviews?

234 patients have reviewed Dr. Karen Burke. The overall rating for this doctor is 4.65/5. They have a 4.78/5 rating for bedside manner and a 4.27/5 rating for wait time. You can read individual reviews and ratings on their profile.

Find doctors